Rapid ultra-performance liquid chromatography assay of losartan potassium in bulk and formulations
Losartan potassium is a non-peptide AT1 receptor drug used in the treatment of hypertension.
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Losartan potassium is a non-peptide AT1 receptor drug used in the treatment of hypertension.
Electrochemical sensors and biosensors for pharmaceutical, food, agricultural and environmental analyses have been growing rapidly due to electrochemical behavior of drugs and biomolecules and partly due to ad...
Histamine was successfully labeled with technetium-99 m (99mTc). The studied reaction parameters included substrate concentration, reducing agent concentration, pH of the reaction mixture, reaction time, in vitro...
Increasing awareness on the environmental impact of heavy metals has increased a considerable interest in the determination of metals in natural water bodies. The present paper describes the development and el...
The present study was carried out to assess the seasonal variations, source apportionment, and risk assessment of heavy metals (Cd, Cr, Cu, Fe, Mn, Pb, and Zn) in the surface sediments from the Khanpur Lake, P...
Humor is composed of a cognitive element related to the detection of humor and an affective element related to the appreciation of humor. To investigate activated areas of the brain related to the two componen...
The Rb-Sr isotope system has long been used for radiometric dating and petrogenetic investigation. The concentrations of Rb and Sr could be precisely measured by isotope dilution thermal ionization mass spectr...
Cetirizine (anti-allergy agent) and non-steroidal anti-inflammatory drugs (NSAIDs; anti-inflammatory agents) are co-administered drugs. Cetirizine, a P-glycopretein substrate may be affected by the use of NSAI...
Ion exchange is one of the widely used techniques in nuclear industries for treatment of liquid radioactive waste. Regular efforts are being made in order to develop new ion exchange resins and their subsequen...
There are many analytical methods available for estimation of glimepiride in biological samples and pharmaceutical preparations. To our knowledge, there is no specific reverse-phase high-performance liquid chr...
A simple, accurate, and reliable high-performance thin-layer chromatography (HPTLC) method was developed for separation and detection of ferulic acid and vanillin.
High-resolution anatomical and functional images can be acquired using high- andultrahigh-field magnetic resonance imaging (MRI) systems. An increase in the mainmagnetic field strength results in high resoluti...
Impurity profiling is now receiving critical attention from regulatoryauthorities. For trace level quantification of potential genotoxic impurities(PGIs), conventional analytical techniques like high-performan...
Postmortem redistribution (PMR) refers to the changes that may occur in drug concentrations after death. Consequently, postmortem concentrations in blood may not always replicate the antemortem drug levels. Liter...
In the present study, the different solvent extracts viz., petroleum ether, chloroform, ethyl acetate and methanol of the medicinal plant Toona ciliata (leaf and flower) were evaluated for phytochemical analysis,...
Pregabalin (PGB), an anticonvulsant, was studied throughout this work using spectrophotometric method.
In the present work, a simple and rapid method for determination of iodate is described.
Chemical compositions and spectroscopic characteristics of the natural floating colloids in brine mineral water were investigated in this study.
The analysis of mercury by cold vapor requires a gas, usually argon or helium, to transport elementary mercury to the gold trap or directly to the detector. When analyzing mercury in environmental matrices, a ...
Nanometer TiO2-Al2O3 composite membranes were synthesized through the sol?gel polymeric reaction of TiCl4 and AlCl3 in the presence of acrylic-acrylamide copolymer as a template. The dried samples were characteri...
Simple and sensitive spectrophotometric method is described based on the reaction of drug (gabapentin) with ninhydrin in pure form and in pharmaceutical preparations.
Eugenol is a potent phytochemical, and a plethora of delivery systems for this bioactive agent is being developed. Reversed-phase high-pressure liquid chromatography equipped with photodiode array detector (RP...
Chronic treatment with fetal bovine serum (FBS) causes gradual vasoconstriction, vascular wall thickening, and contractility reduction in organ-cultured vascular tissues. We have previously demonstrated that R...
Transmission electron microscopy (TEM) is an excellent tool for studying detailed biological structures. High-resolution structure determination is now routinely performed using advanced sample preparation tec...
Direct determination of metal ions, in particular at ultra-trace concentration, cannot be easily achieved in complex systems by analytical techniques because of the lack of sensitivity and selectivity of these...
A novel reverse-phase high-performance liquid chromatography (RP-HPLC)-DAD method was developed, validated and applied to quantify olopatadine hydrochloride in pharmaceutical products.
The study investigated the extent of soil arsenic (As) contamination in agricultural plots in Bengal Delta through contaminated groundwater irrigation. Edaphic levels of As and oxidizable organic carbon (OOC) ...
Amino acids are the building blocks of proteins and found in structural tissues of the human body. Their deficiency may cause a number of diseases.
Tapentadol is a novel centrally acting analgesic. There is no method for the determination of drug content in dosage form without any interference of any excipients and without using the diethylamine content i...
The Sm-Nd isotope system has long been used to provide information on the age and geochemical evolution of terrestrial rocks and extraterrestrial objects. Traditional thermal ionization mass spectrometry requi...
Cryo-electron microscopy is an excellent method for the structural analysis of biological materials. Advantage of its use over conventional electron microscopy techniques is the preservation of the sample in a...
Anaplastic oligodendroglioma (AO) is a type of glioma that is believed to originate from oligodendrocytes in the brain or from glial precursor cells. Recurrence of AO reduces the overall survival rate of patie...
Certain antidepressant drugs namely Sertraline hydrochloride, Fluoxetine hydrochloride, Paroxetine hydrochloride, Thioridazine hydrochloride and Amineptine hydrochloride were studied throughout this work using...
Saccharin, a low calorie artificial sweetener was found as a new diluent / adulterant present along with paracetamol and phenacetin in an illicit methaqualone sample.
Many analytical methods are available for detection of methyl parathion in water but they are not handy for on-site analysis. An attempt has been made to utilize stable GNP for methyl parathion detection by se...
Grx2 is a glutaredoxin from gram positive bacterium Clostridium oremlandii (strain OhILAs), which is Cys-homolog of selenoprotein Grx1. Grx2 is a poor reductant of selenoprotein MsrA not like Grx1 while the reduc...
The Lu-Hf isotope system is widely used to decipher the crustal evolution and mantle differentiation of the Earth. The most critical point in obtaining accurate Hf isotope data is to correct the isobaric inter...
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