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Liraglutide is a glucagon-like peptide-1 (GLP-1) analog that has been utilized for the treatment of type 2 diabetes mellitus. Liraglutide at a higher dose also shows beneficial effects in weight loss, which pr...
Synthetic and natural cannabinoid derivatives are highly investigated as drug candidates due to their antinociceptive, antiepileptic and anticancer potential. Arachidonoylcyclopropylamide (ACPA) is a synthetic...
This study aimed to evaluate whether the use of a high-dielectric pad is effective in increasing transmit and receive sensitivity in areas of low signal intensity in the human brain at high magnetic fields and...
Heavy metal ion pollution is always a serious problem worldwide. Therefore, monitoring heavy metal ions in environmental water is a crucial and difficult step to ensure the safety of people and the environment...
A capillary gas chromatographic method using flame ionization detection was developed and validated for the trace quantification of 2-bromoethanol (2-BE) and 2-bromoethylmethanesulfonate (2-BEM) in silodosin, ...
Hedera nepalensis is commonly used as a traditional medicine for the treatment of several diseases. In this research, the efficient characterization of chemical constituents, especially triterpenoid saponins, con...
The halal food industries are rapidly expanding to fulfill global halal demands. Non-halal substances such as porcine proteins are often added intentionally or unintentionally to products. The development of h...
The present work deals with the synthesis of biodegradable hydrogel of a natural polysaccharide aloe vera and vinyl monomer acrylic acid. In this synthesis, ammonium persulfate–glutaraldehyde was used as initi...
Sarcopenia, characterized by reduced muscle mass and fiber number leading to muscular atrophy, has been associated with serious socioeconomic challenges among the elderly in developed countries. Therefore, pre...
Electrochemical measurements using an agarose hydrogel as a solid electrolyte and ferrocyanide as a redox probe were conducted to analyze transport properties and natural convection effects. The mass transport...
This paper describes a simple electrochemical sensing platform based on single-walled carbon nanotube (SWCNT) electrodes for glucose detection. The device fabrication using O2-plasma treatment allows precision an...
Venadaparib (VEN), a next-generation inhibitor of poly (ADP-ribose) polymerases, is under development for oral use in patients having cancers with deoxyribonucleic acid repair defects. The objective of this st...
Titanium dioxide (TiO2) nanorods (NRs) are well-known semiconducting and catalytic material that has been widely applied, but their toxicities have also attracted recent interest. In this study, we investigated a...
Sensitive and reliable determination of thrombin is relevant in the realms of medical and biological research as it serves as an essential biomarker of a number of blood-related illnesses. Herein, we integrate...
For the clinical diagnosis of diseases and for basic biological research, it is crucial to develop a trustworthy and efficient method for detecting small extracellular vesicles (sEVs) in multiple experimental ...
Multivitamin tablet certified reference material (CRM, 108-10-019) was developed for the analysis of seven water-soluble vitamins, including thiamine, riboflavin, nicotinamide, pantothenic acid, pyridoxine, bi...
In this study, the removal of bisphenol A (BPA), 2,4-dinitrophenol (2,4-DNP), and 2,4-dichlorophenol (2,4-DCP) using a new magnetic adsorbent methacrylic acid-functionalized β-cyclodextrin (Fe3O4@MAA-βCD) was eva...
We report the electronic absorption spectroscopy of 7,7,8,8-tetracyanoquinodimethane (TCNQ) and its fluorinated derivatives (F2TCNQ and F4TCNQ), well-known electron-accepting molecules in common organic solven...
Parkinson’s disease (PD) is the second-most common neurodegenerative disease worldwide. Several studies have investigated PD for decades; however, the exact mechanism of disease development remains unknown. To...
A powder of titanium oxide nanoparticles (TiO2 NPs) was synthesized in this study by anodizing in 0.7 M HClO4 and then annealing in N2 at 450 °C for 3 h to produce TiO2 NPs-N2 powder as a catalyst. These TiO2 NPs...
A magnesium hydroxide co-precipitation sorbent-based method in the presence of an anionic surfactant (e.g., sodium dodecylbenzenesulfonate) and high-performance liquid chromatography were used to preconcentrat...
Photocatalyst oxides added with silicon improve their photocatalytic properties. In this research, nanostructured β-Bi2O3/SiO2 and β-Bi2O3/Bi2O2.75/SiO2 were obtained by means of a green method mediated by the us...
Mackinawite (FeS) was investigated for cadmium ion (Cd(II)) sorption under anoxic conditions. At the surface loading of Cd(II) (i.e., [Cd(II)]0/[FeS]0) ≤ 5 mmol/g, FeS quantitatively immobilized Cd(II). Adsorptio...
In the present research, brewed tea waste (BTW) was utilized as a green, low-priced, and abundant adsorbent for separation/preconcentration of Cd(II) ions through solid-phase extraction method from water and f...
The sensitive and precise quantitative determination of thrombin is important for both fundamental research and clinical diagnostics of hypoxic ischemic encephalopathy because it is a key biological molecule i...
To fundamentally explore the correlation between crop nutritional quality and mineral elements, specific tests and accurate analysis were carried out on all organs and root soil of watermelon (Citrullus lanatus)....
A microextraction procedure that is rapid and simple to extract and preconcentrate ketoprofen and naproxen is proposed. An environmentally friendly supramolecular solvent was applied as an extraction solvent a...
BP100 is a short cationic antimicrobial peptide (AMP) designed using a combinatorial chemistry approach based on the cecropin A-melittin hybrid. It displays potent antimicrobial activity against gram-negative ...
The toxicity and biological activity of arsenic depend on its chemical form. In particular, inorganic arsenics are more toxic than organic ones. Apart from the determination of total arsenics, their accurate s...
We provide a technical report on designing an Arduino-based wireless spectrometer using an old spectrometer. The designed spectrometer is environmentally friendly and cost-effective and can be used in physical...
A one-step immunoassay is presented for the detection of ochratoxin A (OTA) using an antibody complex with switching peptides. Because the switching peptides (fluorescence-labeled) were able to bind the frame ...
Decarboxylation of cannabidiolic acid (CBDA) is an important step for efficient production of the active pharmaceutical component cannabidiol (CBD) in Cannabis species. Acidic cannabinoids (ACBs) can be easily tr...
Mefatinib (MET306) is a novel second-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) designed to address the highly unmet clinical need of gefitinib-induced resistance and irre...
The zinc micronutrient fertilizers have a critical impact on the grain productivity and quality attributes of maize. However, the low use-efficiency issues of the applied Zn-fertilizers are required to be addr...
Natural product like Terminalia chebula as Fe2+ and Fe3+ ions sensor was not reported in the literature till now. Herein, we first reported Terminalia chebula (T. chebula), a natural product used in Ayurveda, as ...
Fatty liver disease is caused by lipid accumulation in the liver, insulin resistance (IR), reactive oxygen species (ROS), and endoplasmic reticulum (ER) stress. Dehydrocostus lactone (DHE) has anticancer, anti...
Early diagnosis and treatment are critical for improving the survival of patients with lung cancer, which is the leading cause of cancer-related deaths worldwide. In this study, we investigated whether the met...
Lung cancer is the second most commonly reported type of cancer worldwide. Approximately 80–85% of lung cancer occurrences are accounted by non-small cell lung cancer (NSCLC). Polo-like kinase-1 (Plk1) plays m...
Miniaturized electrochemical sensing systems are employed in day-to-day uses in the several area from public health to scientific applications. A variety of electrochemical sensor and biosensor systems may not...
Monazite, a moderately common light rare earth element (LREE) and thorium phosphate mineral, has chemical, age, and isotopic characteristics that are useful in the investigation of the origin and evolution of ...
Sensitive quantification of microRNA (miRNA) plays a crucial role in early diagnosis and precise therapy of osteosarcoma. Herein, we build a label-free and sensitive miRNA quantification approach based on the ...
Adenosine triphosphate (ATP) is closely associated with a variety of pathophysiological process, providing energy for cell activities. However, it remains a huge challenge to develop a simple and sensitive ATP...
Alpelisib is the first alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor indicated for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative, PI3K catalytic ...
The amount of silicon in naphtha must be controlled because it results in silica deposits in vehicle components, such as spark plugs, catalytic converters, and oxygen sensors, which can lead to fuel economy de...
Sensitive and reliable analysis of alkylphosphonic acids (APAs) and 2-(N,N-dialkylamino)ethanesulfonic acids (SAs), the degradation products of chemical warfare agents (CWAs), is one of the most important tasks f...
Magnetic nanoparticles (MNPs) provide a fast, cost-effective, and organic-free method for DNA isolation. In this paper, we synthesized MNP coated with oleic acid (Fe3O4@OA) and silica nanoparticles (Fe3O4@OA@SiO2
Mycotoxins are highly toxic fungal metabolites that can pose health threats to humans and animals. Aflatoxins are a type of mycotoxin produced mainly by Aspergillus flavus and A. parasiticus. A sensitive high per...
Development of novel miRNA detection strategies plays a crucial role in fundamental research and clinical diagnosis of various diseases, such as infantile pneumonia. We herein develop a rapid and sensitive DNA...
In biology, evolutionary conserved protein sequences show homologous physiological phenotypes in their structures and functions. If the protein has a vital function, its sequence is usually conserved across th...
To deduce the process of bruise and reduce the number of bruised fruits from the source, the storage time of yellow peaches after bruise should be identified. In order to distinguish the different storage time...
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