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Venadaparib (VEN), a next-generation inhibitor of poly (ADP-ribose) polymerases, is under development for oral use in patients having cancers with deoxyribonucleic acid repair defects. The objective of this st...
Titanium dioxide (TiO2) nanorods (NRs) are well-known semiconducting and catalytic material that has been widely applied, but their toxicities have also attracted recent interest. In this study, we investigated a...
Sensitive and reliable determination of thrombin is relevant in the realms of medical and biological research as it serves as an essential biomarker of a number of blood-related illnesses. Herein, we integrate...
For the clinical diagnosis of diseases and for basic biological research, it is crucial to develop a trustworthy and efficient method for detecting small extracellular vesicles (sEVs) in multiple experimental ...
Multivitamin tablet certified reference material (CRM, 108-10-019) was developed for the analysis of seven water-soluble vitamins, including thiamine, riboflavin, nicotinamide, pantothenic acid, pyridoxine, bi...
In this study, the removal of bisphenol A (BPA), 2,4-dinitrophenol (2,4-DNP), and 2,4-dichlorophenol (2,4-DCP) using a new magnetic adsorbent methacrylic acid-functionalized β-cyclodextrin (Fe3O4@MAA-βCD) was eva...
We report the electronic absorption spectroscopy of 7,7,8,8-tetracyanoquinodimethane (TCNQ) and its fluorinated derivatives (F2TCNQ and F4TCNQ), well-known electron-accepting molecules in common organic solven...
Parkinson’s disease (PD) is the second-most common neurodegenerative disease worldwide. Several studies have investigated PD for decades; however, the exact mechanism of disease development remains unknown. To...
A powder of titanium oxide nanoparticles (TiO2 NPs) was synthesized in this study by anodizing in 0.7 M HClO4 and then annealing in N2 at 450 °C for 3 h to produce TiO2 NPs-N2 powder as a catalyst. These TiO2 NPs...
A magnesium hydroxide co-precipitation sorbent-based method in the presence of an anionic surfactant (e.g., sodium dodecylbenzenesulfonate) and high-performance liquid chromatography were used to preconcentrat...
Photocatalyst oxides added with silicon improve their photocatalytic properties. In this research, nanostructured β-Bi2O3/SiO2 and β-Bi2O3/Bi2O2.75/SiO2 were obtained by means of a green method mediated by the us...
Mackinawite (FeS) was investigated for cadmium ion (Cd(II)) sorption under anoxic conditions. At the surface loading of Cd(II) (i.e., [Cd(II)]0/[FeS]0) ≤ 5 mmol/g, FeS quantitatively immobilized Cd(II). Adsorptio...
In the present research, brewed tea waste (BTW) was utilized as a green, low-priced, and abundant adsorbent for separation/preconcentration of Cd(II) ions through solid-phase extraction method from water and f...
The sensitive and precise quantitative determination of thrombin is important for both fundamental research and clinical diagnostics of hypoxic ischemic encephalopathy because it is a key biological molecule i...
To fundamentally explore the correlation between crop nutritional quality and mineral elements, specific tests and accurate analysis were carried out on all organs and root soil of watermelon (Citrullus lanatus)....
A microextraction procedure that is rapid and simple to extract and preconcentrate ketoprofen and naproxen is proposed. An environmentally friendly supramolecular solvent was applied as an extraction solvent a...
BP100 is a short cationic antimicrobial peptide (AMP) designed using a combinatorial chemistry approach based on the cecropin A-melittin hybrid. It displays potent antimicrobial activity against gram-negative ...
The toxicity and biological activity of arsenic depend on its chemical form. In particular, inorganic arsenics are more toxic than organic ones. Apart from the determination of total arsenics, their accurate s...
We provide a technical report on designing an Arduino-based wireless spectrometer using an old spectrometer. The designed spectrometer is environmentally friendly and cost-effective and can be used in physical...
A one-step immunoassay is presented for the detection of ochratoxin A (OTA) using an antibody complex with switching peptides. Because the switching peptides (fluorescence-labeled) were able to bind the frame ...
Decarboxylation of cannabidiolic acid (CBDA) is an important step for efficient production of the active pharmaceutical component cannabidiol (CBD) in Cannabis species. Acidic cannabinoids (ACBs) can be easily tr...
Mefatinib (MET306) is a novel second-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) designed to address the highly unmet clinical need of gefitinib-induced resistance and irre...
The zinc micronutrient fertilizers have a critical impact on the grain productivity and quality attributes of maize. However, the low use-efficiency issues of the applied Zn-fertilizers are required to be addr...
Natural product like Terminalia chebula as Fe2+ and Fe3+ ions sensor was not reported in the literature till now. Herein, we first reported Terminalia chebula (T. chebula), a natural product used in Ayurveda, as ...
Fatty liver disease is caused by lipid accumulation in the liver, insulin resistance (IR), reactive oxygen species (ROS), and endoplasmic reticulum (ER) stress. Dehydrocostus lactone (DHE) has anticancer, anti...
Early diagnosis and treatment are critical for improving the survival of patients with lung cancer, which is the leading cause of cancer-related deaths worldwide. In this study, we investigated whether the met...
Lung cancer is the second most commonly reported type of cancer worldwide. Approximately 80–85% of lung cancer occurrences are accounted by non-small cell lung cancer (NSCLC). Polo-like kinase-1 (Plk1) plays m...
Miniaturized electrochemical sensing systems are employed in day-to-day uses in the several area from public health to scientific applications. A variety of electrochemical sensor and biosensor systems may not...
Monazite, a moderately common light rare earth element (LREE) and thorium phosphate mineral, has chemical, age, and isotopic characteristics that are useful in the investigation of the origin and evolution of ...
Sensitive quantification of microRNA (miRNA) plays a crucial role in early diagnosis and precise therapy of osteosarcoma. Herein, we build a label-free and sensitive miRNA quantification approach based on the ...
Adenosine triphosphate (ATP) is closely associated with a variety of pathophysiological process, providing energy for cell activities. However, it remains a huge challenge to develop a simple and sensitive ATP...
Alpelisib is the first alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor indicated for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative, PI3K catalytic ...
The amount of silicon in naphtha must be controlled because it results in silica deposits in vehicle components, such as spark plugs, catalytic converters, and oxygen sensors, which can lead to fuel economy de...
Sensitive and reliable analysis of alkylphosphonic acids (APAs) and 2-(N,N-dialkylamino)ethanesulfonic acids (SAs), the degradation products of chemical warfare agents (CWAs), is one of the most important tasks f...
Magnetic nanoparticles (MNPs) provide a fast, cost-effective, and organic-free method for DNA isolation. In this paper, we synthesized MNP coated with oleic acid (Fe3O4@OA) and silica nanoparticles (Fe3O4@OA@SiO2
Mycotoxins are highly toxic fungal metabolites that can pose health threats to humans and animals. Aflatoxins are a type of mycotoxin produced mainly by Aspergillus flavus and A. parasiticus. A sensitive high per...
Development of novel miRNA detection strategies plays a crucial role in fundamental research and clinical diagnosis of various diseases, such as infantile pneumonia. We herein develop a rapid and sensitive DNA...
In biology, evolutionary conserved protein sequences show homologous physiological phenotypes in their structures and functions. If the protein has a vital function, its sequence is usually conserved across th...
To deduce the process of bruise and reduce the number of bruised fruits from the source, the storage time of yellow peaches after bruise should be identified. In order to distinguish the different storage time...
Due to the widespread emergence of COVID-19, face masks have become a common tool for reducing transmission risk between people, increasing the need for sterilization methods against mask-contaminated microorg...
Metal–organic frameworks (MOFs) with high stability and porosity have gained great attention in bioanalysis due to their potential in improving sensitivity and robustness of assays. Herein, to improve both the...
Cellulases are a group of enzymes, which catalyse different steps of cellulose hydrolysis, and are broadly used in industry as unpurified mixtures of several enzymes. The total activity of cellulase is defined...
Extracellular matrix (ECM) proteins play a pivotal role in cell growth and differentiation. To characterize aged ECM proteins, we compared the proteomes by shotgun method of young (passage #15) and late senesc...
The morphology of a material is considered one of the primary aspects affecting its photocatalytic performance. Various methods have been developed to tailor the morphology of photocatalytic materials for phot...
In this paper, the combined terahertz time-domain spectroscopy (THz-TDS) and chemometrics method is proposed to identify four different parts of Panax notoginseng rapidly and nondestructively. The research object...
One of the major applications of zinc dialkyldithiophosphates (ZnDDPs) is their usage as an anti-wear additive in lubricants including greases, hydraulic oils, and motor oils. ZnDDPs also could be used as corr...
This study investigated the electric field distribution of underground cable insulation in cross-linked polyethylene/zinc oxide (XLPE/ ZnO) nanoparticles (NPs) for medium-voltage (MV) cables. The ZnO NPs that ...
The adsorption efficiency of Pb(II) and Cd(II) from aqueous solutions on m-phenylenediamine-modified Amberlite XAD-4 resin was investigated. The effects of pH, adsorbent amount, initial metal concentration, el...
In a transmission electron microscope (TEM), the objective lens (OL) is the most important component because the first image and diffraction pattern for a specimen are formed by applying a specific OL current ...
In this paper, we evaluated the effect of seven stabilizers with different shapes (including cylinder, cubic and ball shape) on zircon U–Pb dating analysis by laser ablation inductively coupled plasma quadrupo...
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