Andrade PD, da Silva JLG, Caldas ED. Simultaneous analysis of aflatoxins B1, B2, G1, G2, M1 and ochratoxin A in breast milk by high-performance liquid chromatography/fluorescence after liquid–liquid extraction with low temperature purification (LLE–LTP). J Chromatogr A. 2013;1304:61–8. https://doi.org/10.1016/j.chroma.2013.06.049.
Article
CAS
PubMed
Google Scholar
Ardic M, Karakaya Y, Atasever M, Durmaz H. Determination of aflatoxin B1 levels in deep-red ground pepper (isot) using immunoaffinity column combined with ELISA. Food Chem Toxicol. 2008;46:1596–9. https://doi.org/10.1016/j.fct.2007.12.025.
Article
CAS
PubMed
Google Scholar
Arroyo-Manzanares N, Campillo N, López-García I, Hernández-Córdoba M, Viñas P. High-Resolution mass spectrometry for the determination of mycotoxins in biological samples: a review. Microchem J. 2021;166:106197. https://doi.org/10.1016/j.microc.2021.106197.
Article
CAS
Google Scholar
Bastaki SA, Osman N, Kochiyil J, Shafiullah M, Padmanabhan R, Abdulrazzaq YM. Toxicokinetics of Aflatoxin in Pregnant Mice. Int J Toxicol. 2010;29:425–31. https://doi.org/10.1177/1091581810369565.
Article
CAS
PubMed
Google Scholar
Bastianello SS, Nesbit JW, Williams MC, Lange AL. Pathological findings in a natural outbreak of aflatoxicosis in dogs. Onderstepoort J Vet Res. 1987;54:635–640. https://doi.org/10.1080/00480169./1987.35460.
Benkerroum N. Aflatoxins: producing-molds, structure, health issues and incidence in southeast Asian and sub-Saharan African countries. Int J Environ Res Public Health. 2020;17:1215. https://doi.org/10.3390/ijerph17041215.
Article
PubMed
PubMed Central
Google Scholar
Bianco G, Russo R, Marzocco S, Velotto S, Autore G, Severino L. Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2. Toxicon. 2012;59:644–50. https://doi.org/10.1016/j.toxicon.2012.02.010.
Article
CAS
PubMed
Google Scholar
Bruchim Y, Segev G, Sela U, Bdolah-Abram T, Salomon A, Aroch I. Accidental fatal aflatoxicosis due to contaminated commercial diet in 50 dogs. Res Vet Sci. 2012;93:279–87. https://doi.org/10.1016/j.rvsc.2011.07.024.
Article
CAS
PubMed
Google Scholar
Cao X, Li X, Li J, Niu Y, Shi L, Fang Z, Zhang T, Ding H. Quantitative determination of carcinogenic mycotoxins in human and animal biological matrices and animal-derived foods using multi-mycotoxin and analyte-specific high performance liquid chromatography-tandem mass spectrometric methods. J Chromatogr B. 2018;1073:191–200. https://doi.org/10.1016/j.jchromb.2017.10.006.
Article
CAS
Google Scholar
Chao TC, Maxwell SM, Wong SY. An outbreak of aflatoxicosis and boric acid poisoning in Malaysia: a clinicopathological study. J Pathol. 1991;164:225–33. https://doi.org/10.1002/path.1711640307.
Article
CAS
PubMed
Google Scholar
Chen Z, Ying S, Liu J, Zhan P, Zhao Y. PRiME pass-through cleanup for the fast determination of aflatoxins in human serum by using LC-MS/MS. Anal Methods. 2016;8:1457–62. https://doi.org/10.1039/c5ay03099d.
Article
CAS
Google Scholar
De Santis B, Raggi ME, Moretti G, Facchiano F, Mezzelani A, Villa L, Bonfanti A, Campioni A, Rossi S, Camposeo S, Soricelli S, Moracci G, Debegnach F, Gregori E, Ciceri F, Milanesi L, Marabotti A, Brera C. Study on the association among mycotoxins and other variables in children with Autism. Toxins. 2017. https://doi.org/10.3390/toxins9070203.
Article
PubMed
PubMed Central
Google Scholar
Devreese M, De Baere S, De Backer P, Croubels S. Quantitative determination of several toxicological important mycotoxins in pig plasma using multi-mycotoxin and analyte-specific high performance liquid chromatography–tandem mass spectrometric methods. J Chromatogr A. 2012;1257:74–80. https://doi.org/10.1016/j.chroma.2012.08.008.
Article
CAS
PubMed
Google Scholar
Ediage EN, Mavungu J, Song S, Wu A, Peteghem CV, Saeger SD. A direct assessment of mycotoxin biomarkers in human urine samples by liquid chromatography tandem mass spectrometry. Anal Chim Acta. 2012;741:58–69. https://doi.org/10.1016/j.aca.2012.06.038.
Article
CAS
PubMed
Google Scholar
Fan K, Xu J, Jiang K, Liu X, Meng J, Di Mavungu JD, Guo W, Zhang Z, Jing J, Li H, Yao B, Li H, Zhao Z, Han Z. Determination of multiple mycotoxins in paired plasma and urine samples to assess human exposure in Nanjing, China. Environ Pollut. 2019;248:865–73. https://doi.org/10.1016/j.envpol.2019.02.091.
Article
CAS
PubMed
Google Scholar
Gallo A, Moschini M, Masoero F. Aflatoxins absorption in the gastro-intestinal tract and in the vaginal mucosa in lactating dairy cows. Ital J Anim Sci. 2008;7:53–63. https://doi.org/10.4081/ijas.2008.53.
Article
Google Scholar
Han Z, Zhao Z, Song S, Liu G, Shi J, Zhang J, Liao Y, Zhang D, Wu Y, Saeger S, Wu A. Establishment of an isotope dilution LC-MS/MS method revealing kinetics and distribution of co-occurring mycotoxins in rats. Anal Methods. 2012;4:3708–17. https://doi.org/10.1039/C2AY25891A.
Article
CAS
Google Scholar
Huang W, Liu M, Xiao B, Zhang J, Song M, Li Y, Cao Z. Aflatoxin B1 disrupts blood-testis barrier integrity by reducing junction protein and promoting apoptosis in mice testes. Food Chem Toxicol. 2021;148:111972. https://doi.org/10.1016/j.fct.2021.111972.
Article
CAS
PubMed
Google Scholar
Jubert C, Mata J, Bench G, Dashwood R, Pereira C, Tracewell W, Turteltaub K, Williams D, Bailey G. Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B1 pharmacokinetics in human volunteers. Cancer Prev Res Phila. 2009;2:1015–22. https://doi.org/10.1158/1940-6207.capr-09-0099.
Article
CAS
PubMed
PubMed Central
Google Scholar
Klvana M, Bren U. Aflatoxin B1–Formamidopyrimidine DNA adducts: relationships between structures, free energies, and melting temperatures. Molecules. 2019;24:150. https://doi.org/10.3390/molecules24010150.
Article
CAS
PubMed Central
Google Scholar
Marchese S, Polo A, Ariano A, Velotto S, Costantini S, Severino L. Aflatoxin B1 and M1: biological properties and their involvement in cancer development. Toxins. 2018. https://doi.org/10.3390/toxins10060214s.
Article
PubMed
PubMed Central
Google Scholar
Martínez-Martínez L, Valdivia-Flores AG, Guerrero-Barrera AL, Quezada-Tristán T, Rangel-Muñoz EJ, Ortiz-Martínez R. Toxic effect of aflatoxins in dogs fed contaminated commercial dry feed: a review. Toxins. 2021. https://doi.org/10.3390/toxins13010065.
Article
PubMed
PubMed Central
Google Scholar
Martins C, Vidal A, De Boevre M, De Saeger S, Nunes C, Torres D, Goios A, Lopes C, Alvito P, Assunção R. Burden of disease associated with dietary exposure to carcinogenic aflatoxins in Portugal using human biomonitoring approach. Food Res Int. 2020;134:109210. https://doi.org/10.1016/j.foodres.2020.109210.
Article
CAS
PubMed
Google Scholar
Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC−MS/MS. Anal Chem. 2003;75:3019–30. https://doi.org/10.1021/ac020361s.
Article
CAS
PubMed
Google Scholar
McKean C, Tang L, Billam M, Tang M, Theodorakis CW, Kendall RJ, Wang JS. Comparative acute and combinative toxicity of aflatoxin B1 and T-2 toxin in animals and immortalized human cell lines. J Appl Toxicol. 2006;26:139–47. https://doi.org/10.1002/jat.1117.
Article
CAS
PubMed
Google Scholar
McMillan A, Renaud JB, Burgess KMN, Orimadegun AE, Akinyinka OO, Allen SJ, Miller JD, Reid G, Sumarah MW. Aflatoxin exposure in Nigerian children with severe acute malnutrition. Food Chem Toxicol. 2018;111:356–62. https://doi.org/10.1016/j.fct.2017.11.030.
Article
CAS
PubMed
Google Scholar
Mupunga I, Izaaks CD, Shai LJ, Katerere DR. Aflatoxin biomarkers in hair may facilitate long‐term exposure studies. J Appl Toxicol. 2016;37:395–9. https://doi.org/10.1002/jat.3422.
Article
CAS
PubMed
Google Scholar
Neal GE, Eaton DL, Judah DJ, Verma A. Metabolism and toxicity of aflatoxins M1and B1in human-derivedin vitrosystems. Toxicol Appl Pharmacol. 1998;151:152–8. https://doi.org/10.1006/taap.1998.8440.
Article
CAS
PubMed
Google Scholar
Osteresch B, Viegas S, Cramer B, Humpf H-U. Multi-mycotoxin analysis using dried blood spots and dried serum spots. Anal Bioanal Chem. 2017;409:3369–82. https://doi.org/10.1007/s00216-017-0279-9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Peters FT, Drummer OH, Musshoff F. Validation of new methods. Forensic Sci Int. 2007;165:216–24. https://doi.org/10.1016/j.forsciint.2006.05.021.
Article
CAS
PubMed
Google Scholar
Qi D, Fei T, Liu H, Yao H, Wu D, Liu B. Development of multiple heart-cutting two-dimensional liquid chromatography coupled to quadrupole-orbitrap high resolution mass spectrometry for simultaneous determination of aflatoxin B1, B2, G1, G2, and ochratoxin A in snus, a smokeless tobacco product. J Agric Food Chem. 2017;65:9923–9. https://doi.org/10.1021/acs.jafc.7b04329.
Article
CAS
PubMed
Google Scholar
Ramos AJ, Hernández E. In situ absorption of aflatoxins in rat small intestine. Mycopathologia. 1996;134:27–30. https://doi.org/10.1007/BF00437049.
Article
CAS
PubMed
Google Scholar
Rubert J, León N, Sáez C, Martins CPB, Godula M, Yusà V, Mañes J, Soriano JM, Soler C. Evaluation of mycotoxins and their metabolites in human breast milk using liquid chromatography coupled to high resolution mass spectrometry. Anal Chim Acta. 2014;820:39–46. https://doi.org/10.1016/j.aca.2014.02.009.
Article
CAS
PubMed
Google Scholar
Schrenk D, Bignami M, Bodin L, Chipman J, del Mazo J, Grasl-Kraupp B, Hogstrand C, Hoogenboom L, Leblanc J-C, Nebbia C, Nielsen E, Ntzani E, Petersen A, Sand S, Schwerdtle T, Vleminckx C, Marko D, Oswald I, Piersma A, Wallace H, Risk assessment of aflatoxins in food. EFSA J. 2020; 18:e06040. https://doi.org/10.2903/j.efsa.2020.6040
Seetha A, Monyo ES, Tsusaka TW, Msere HW, Madinda F, Chilunjika T, Sichone E, Mbughi D, Chilima B, Matumba L. Aflatoxin-lysine adducts in blood serum of the Malawian rural population and aflatoxin contamination in foods (groundnuts, maize) in the corresponding areas. Mycotoxin Res. 2018;34:195–204. https://doi.org/10.1007/s12550-018-0314-5.
Article
CAS
PubMed
Google Scholar
Slobodchikova I, Vuckovic D. Liquid chromatography – high resolution mass spectrometry method for monitoring of 17 mycotoxins in human plasma for exposure studies. J Chromatogr A. 2018;1548:51–63. https://doi.org/10.1016/j.chroma.2018.03.030.
Article
CAS
PubMed
Google Scholar
Tkaczyk A, Jedziniak P. Development of a multi-mycotoxin LC-MS/MS method for the determination of biomarkers in pig urine. Mycotoxin Res. 2021;37:169–81. https://doi.org/10.1007/s12550-021-00428-w.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wogan GN, Paglialunga S. Carcinogenicity of synthetic aflatoxin M1 in rats. Food Cosmet Toxicol. 1974;12:381–4. https://doi.org/10.1016/0015-6264(74)90012-1.
Article
CAS
PubMed
Google Scholar
Wong ZA, Hsieh DPH. The comparative metabolism and toxicokinetics of aflatoxin B1 in the monkey, rat, and mouse. Toxicol Appl Pharmacol. 1980;55:115–25. https://doi.org/10.1016/0041-008X(80)90227-6.
Article
CAS
PubMed
Google Scholar
Xia L, Routledge M, Rasheed H, Ismail A, Dong Y, Jiang T, Gong YY. Biomonitoring of aflatoxin B1 and deoxynivalenol in a rural pakistan population using ultra-sensitive LC-MS/MS method. Toxins. 2020;12:591. https://doi.org/10.3390/toxins12090591.
Article
CAS
PubMed Central
Google Scholar