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Table 2 Extraction efficiency (n = 3) and matrix effects (n = 3) for the analysis of bromophenol-thiosemicarbazone hybrid in rat plasma

From: An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study

Nominal concentration (nmol/L)

Extraction efficacy (%)

Matrix effects (%)

Mean ± SD (RSD)

Mean ± SD (RSD)

100

108 ± 12 (11)

73.5 ± 9.6 (13)

1000

114 ± 2 (2)

110 ± 3 (2)

10000

119 ± 1 (1)

115 ± 1 (1)