Table 2 Concentration of opioids and benzodiazepines in patient urine samples
Patient | Prescriptions | Expected compounds | Detected compounds and metabolites | LLOQ (ng/mL) | HLOQ (ng/mL) | Concentrations [ng/mL] | Change c | |
|---|---|---|---|---|---|---|---|---|
Initial a | Final b | |||||||
I | OxyIR® | Morphine, oxycodone | 6-Acetylmorphine | 3 | 192 | 17 | 9 | − |
Hydromorphone | 100 | 6,400 | 639 | 900 | + | |||
Morphine | 100 | 6,400 | (91,475) | (146,125) | ||||
Oxycodone | 50 | 3,200 | (8,525) | (12,346) | ||||
Oxymorphone | 100 | 6,400 | 1,432 | 2,426 | + | |||
Nordiazepam | 80 | 5,120 | 4,147 | 4,092 | − | |||
Oxazepam | 80 | 5,120 | 4,830 | 4,684 | − | |||
80 | 5,120 | 3,630 | 2,469 | − | ||||
II | Opana®, oxycodone | Oxymorphone, oxycodone | Buprenorphine | 10 | 640 | 23 | 24 | + |
Norbuprenorphine | 20 | 1,280 | 94 | 86 | − | |||
Oxycodone | 50 | 3,200 | (13,076) | (23,402) | ||||
Oxymorphone | 100 | 6,400 | (10,109) | (15,006) | ||||
Alpha hydroxyl alprazolam | 80 | 5,120 | 620 | 528 | − | |||
Alprazolam | 80 | 5,120 | 163 | 154 | − | |||
III | Lortab®, Percocet®, Soma®, Valium® | Hydrocodone, acetaminophen, oxycodone, carisoprodol, diazepam | Hydrocodone | 100 | 6,400 | 5,988 | 4,801 | − |
Hydromorphone | 100 | 6,400 | 207 | 259 | + | |||
Oxycodone | 50 | 3,200 | 3,197 | 2,941 | − | |||
Oxymorphone | 100 | 6,400 | 365 | 774 | + | |||
Alpha hydroxyl alprazolam | 80 | 5,120 | 133 | 57 | − | |||
Nordiazepam | 80 | 5,120 | 1,733 | 1,533 | − | |||
Oxazepam | 80 | 5,120 | (6,604) | (5,646) | ||||
Temazepam | 80 | 5,120 | 3,891 | 2,953 | − | |||
IV | Endocet®, Soma®, Xanax® | Oxycodone, acetaminophen, carisoprodo, alprazolam | Oxycodone | 50 | 3,200 | 1,413 | 1,182 | − |
Oxymorphone | 100 | 6,400 | 491 | 803 | + | |||
Alpha hydroxyl alprazolam | 80 | 5,120 | 253 | 161 | − | |||
Alprazolam | 80 | 5,120 | 1,003 | 890 | − | |||
Meprobamate | 100 | 6,400 | (14,016) | (13,838) | ||||