ICH guideline practice: application of validated RP-HPLC-DAD method for determination of tapentadol hydrochloride in dosage form

Journal of Analytical Science and Technology

Table 1 System suitability parameters for TAP

Parameters	Value for TAP ^a	SD	%RSD
Number of theoretical plates	21,930	61.64	0.281
Tailing factor	1.12	0.051	0.956
Capacity factor	16.44	0.222	1.352
RT (min)	5.34	0.037	0.698
Peak purity	1.00	0.000	0.000

RT retention time, SD standard deviation, %RSD percentage of relative standard deviation. ^aMean of six values.