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Journal of Analytical Science and Technology
Fig. 2 | Journal of Analytical Science and Technology

Fig. 2

From: Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges

Fig. 2

A Effects of adduct ions on mass resolving power. Individual simulations of the isotope distributions of unmodified (green), ammonium-bound (orange), and sodium-bound (red) averagine protein ions were combined to create the final mass spectrum (black); B mass spectra of GroEL (+ 71 charged) ions on a QTOF (cyan) and Orbitrap (blue) simulated with MassLynx ver 4.1 at maximum mass resolution of 40,000 (green), 20,000 (yellow), 10,000 (orange), and 5000 (red). The natural isotope envelope of GroEL is denoted with black. Reprinted with permission from Ref (Lössl et al. 2014). Copyright 2014 American Chemical Society

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