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Journal of Analytical Science and Technology
Fig. 18 | Journal of Analytical Science and Technology

Fig. 18

From: Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges

Fig. 18

Native FT-ICR MS spectra of mAb conjugate analyzed over the m/z range of 3500–10500 a 5 M equivalent biotin-lysine conjugate; b 10 M equivalent biotin-lysine conjugate; c 5 M equivalent TCEP, 10 M equivalent biotin-cysteine conjugate; d 10 M equivalent TCEP, 10 M equivalent biotin-cysteine conjugate; DAR values are annotated on selected charge states and all deconvoluted spectra. Reprinted with permission from Ref (Campuzano et al. 2018). Copyright 2017 American Chemical Society

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