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Journal of Analytical Science and Technology
Fig. 12 | Journal of Analytical Science and Technology

Fig. 12

From: Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges

Fig. 12

Spectra produced with short and long response times showed distinct patterns. The spectra were produced by accumulating 200 scans at 240,000 resolving power at 200 m/z using A ETD for 5 ms and B AI-ETD with 18 W laser power for 120 ms. The top spectra's peaks are colored according to their associated charge states. The annotated area between 1500 and 1550 m/z represents the best matching ions for the heavy chain in blue and the light chain in red. NL stands for normalized level. Reprinted with permission from Ref (Lodge et al. 2020). Copyright 2020 American Chemical Society

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