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Table 3 Face-centered CCD matrix with two independent variables studied accompanied by results marked

From: Application of Plackett-Burman and central composite designs for screening and optimization of factor influencing the chromatographic conditions of HPTLC method for quantification of efonidipine hydrochloride

Runs

Development distance (mm)

(X1)

Saturation time (min)

(X2)

Peak area

1

8.0

25

4526.56

2

8.5

20

6512.32

3

7.5

25

5264.65

4

8.0

20

6865.48

5

8.0

20

6795.53

6

8.0

20

6656.69

7

8.0

20

6845.12

8

7.5

15

5156.98

9

7.5

20

5951.18

10

8.5

25

4156.69

11

8.5

15

6965.74

12

8.0

20

6685.48

13

8.0

15

5985.56