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Table 1 Comparison of collision cross section (CCS) and minimum resolution (R) that is required to resolve the peaks of selected isomeric ions in an ion mobility spectrum (R = CCS/ΔCCS). The CCS calculations were carried out by using the ion mobility spectrometry suite (IMoS) via the parallelized user interface (ParsIMoS) (Kune 2018)

From: Enhanced differentiation of isomeric RNA modifications by reducing the size of ions in ion mobility mass spectrometric measurements

Isobaric ions

Calculated CCS (Ă…)

Required resolution

m1A

164.1

36.67

m6A

168.7

m1a

124.7

30.69

m6a

128.9

  1. A adenosine, a adenine, ΔCCS difference between two CCS values