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Table 2 Intra-batch (n = 5) and inter-batch (n = 15) accuracy and precision for the analysis of the five analytes in rat plasma

From: A simplified LC−MS/MS approach for simultaneous quantification and pharmacokinetics of five compounds in rats following oral administration of Gastrodia elata extract

Compounds

Conc. spiked (ng/mL)

Intra-batch data

Inter-batch data

Accuracy (%)

Precision (%CV)

Accuracy (%)

Precision (%CV)

Gastrodin

20

114.5

4.6

111.9

5.9

900

93.6

9.1

93.8

0.4

2700

86.4

3.5

91.5

7.9

Parishin A

5

107.4

9.6

111.9

5.8

100

89.2

8.1

93.9

9.6

300

90.5

5.9

88.8

0.4

Parishin B

5

108.6

4.8

106.3

11.3

100

105.9

4.7

102.6

6.1

300

107.7

3.5

100.4

1.5

Parishin C

5

97.1

3.7

95.0

12.9

100

99.8

2.2

95.4

1.0

300

98.6

5.1

99.9

1.8

Parishin E

5

102.2

14.1

101.0

7.1

900

87.5

13.4

90.4

0.7

2700

100.3

2.5

96.3

5.8