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Table 10 Results of effect of variation in organic (acetonitrile) variation

From: A novel UPLC-PDA isocratic method for the quantification fulvestrant in oil-based pre-filled syringe injection matrix formulations

S. No. Name of the parameter Water:ACN:MeOH (300:400:300) Water:ACN:MeOH (300:360:300) Water:ACN:MeOH (300:440:300)
1 Tailing factor for fulvestrant peak 0.94 0.94 0.95
2 % RSD of fulvestrant peak areas for five replicate injections of standard 0.2 0.1 0.3
3 USP plate count for fulvestrant peak 4229 4263 4002
4 % Assay 101.4 100.7 100.7