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Table 3 Experimental results for the compound C25H25N8O4Cl, HCl

From: Mat-CHN software for drug substance titrations in discovery and development

Analytical determination Method Experimental results (%w/w)
Water content Karl Fischer 0.80
Water content Karl Fischer 0.85
Butanol-1 CPG-head space 0.35 (3500 ppm)
Chloride ion content Ionic chromatography 6.21(1)
Chloride ion content Ionic chromatography 5.82(1)
Chloride ion content Ionic chromatography 6.03(1)
Des-chlorinated Impurity HPLC 0.3
Di-chlorinated Impurity HPLC 0.6
%C Elemental analysis 51.720
%H Elemental analysis 4.708
%N Elemental analysis 19.054
  1. 1As a remainder, each of these individual results will be divided by 3 (three values for the same series of results) for Mat-CHN exploitation