Table 4 Matrix effects for analytes in eight different lots of human plasma
Analyte | LQC analyte average peak area in absence of matrix | LQC analyte average peak area in presence of matrix | LQC matrix factor for analyte | % CV | HQC analyte average peak area in absence of matrix | HQC analyte average peak area in presence of matrix | HQC matrix factor for analyte | % CV |
|---|---|---|---|---|---|---|---|---|
Lamivudine | 33,007 | 31,718 | 96.09 | 1.43 | 1,281,899 | 1,332,156 | 103.92 | 2.09 |
Zidovudine | 6848 | 6721 | 98.15 | 4.24 | 273,050 | 283,906 | 103.98 | 1.68 |
Nevirapine | 57,547 | 54,476 | 94.66 | 1.21 | 2,070,858 | 2,112,144 | 101.99 | 1.66 |