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Table 1 The CCD experimental design and the resultant % ER

From: Vortex-assisted supramolecular solvent dispersive liquid–liquid microextraction of ketoprofen and naproxen from environmental water before chromatographic analysis: response surface methodology optimisation

Run

pH

CS

SV

KET

NAP

1

4

1500

100

92.0

82.9

2

4

1500

800

96.0

102.9

3

4

3500

100

82.0

85.7

4

4

3500

800

88.0

101.7

5

9

1500

100

80.6

88.6

6

9

1500

800

82.5

85.7

7

9

3500

100

71.3

74.3

8

9

3500

800

75.0

91.4

9

3.3

2500

450

93.1

102.9

10

9.7

2500

450

65.3

87.8

11

6.5

1213

450

93.6

96.4

12

6.5

3787

450

91.5

86.8

13

6.5

2500

− 0.5

0.0

0.00

14

6.5

2500

900

95.9

96.5

15

6.5

2500

450

100.2

99.6

16

6.5

2500

450

98.0

102.9