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Journal of Analytical Science and Technology
Fig. 4 | Journal of Analytical Science and Technology

Fig. 4

From: Development and validation of a new LC–MS/MS method for the determination of mefatinib in human plasma and its first application in pharmacokinetic studies

Fig. 4

The mean plasma concentration–time curves of NSCLC patients in different dose groups after multiple dosing of MET306. * The Mean ± SD plasma concentration–time profile of MET306 in human plasma following multiple oral administration of MET306 in different dose groups (A: 10 mg, B: 20 mg, C: 30 mg, D: 45 mg, E: 60 mg, F: 80 mg, G: 105 mg, H: 140 mg) to NSCLC patients (A: n = 1, B: n = 3, C: n = 3, D: n = 4, E: n = 4, F: n = 4, G: n = 5, H: n = 1)

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