Table 2 Analytical features of the IT monolithic μ-SPE coupled with HPLC-UV and UHPLC-Q ExactiveTM Plus Orbitrap HRMS systems
Concentration range (ng mL−1) | tr (min) | Regression equation | r2 | LOD (ng mL−1) | LOQ (ng mL−1) | |
|---|---|---|---|---|---|---|
IT monolithic μ-SPE coupled with HPLC-UV | ||||||
RAC | 25–250 | 5.34±0.68 | y = 0.6323x − 13.351 | 0.9992 | 3.75 | 12.50 |
CLEN | 10–200 | 7.02±0.67 | y = 0.9506x − 4.032 | 0.9999 | 1.88 | 6.25 |
IT monolithic μ-SPE coupled with UHPLC-Q ExactiveTM Plus Orbitrap HRMS | ||||||
RAC | 2–250 | 2.23±0.01 | y = 1804862x + 4137950 | 0.9969 | 0.34 | 1.13 |
CLEN | 0.8–200 | 3.31±0.01 | y = 2765788x + 9745616 | 0.9947 | 0.19 | 0.65 |