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Table 3 System suitability study results

From: LC-Q-TOF-MS driven identification of potential degradation impurities of venetoclax, mechanistic explanation on degradation pathway and establishment of a quantitative analytical assay method

System suitability (at 100% level )

Injections

Area

Asymmetry

Retention time

Theoretical plates

S1

16226464

0.96

22.36

73017

S2

15899107

0.95

22.44

72460

S3

16026113

0.97

22.48

72671

S4

15910984

0.95

22.44

73197

S5

16152639

0.98

22.38

73072

S6

16208396

0.96

22.34

73785

Average

16070617.17

0.96

22.41

73033.67

SD

146203.92

0.01

0.05

459.03

% RSD

0.91%

1.22%

0.24%

0.63%