Parameters | HPTLC |
---|---|
Linearity | |
Range (ng/band) | 300–1800 |
Slope | 4.812 |
Intercept | 506.5 |
Correlation coefficient | 0.999 |
Accuracy | |
% recovery (% RSD) | 98.57–101.40%, 0.34–0.75 |
Precision | |
Intra-day precision (n = 3) (% RSD) | 0.41–1.54 |
Inter-day precision (n = 3) (% RSD) | 1.14–1.66 |
Repeatability (n = 6) (% RSD) | 0.65 |
Sensitivity | |
Limit of detection (ng) | 10.41 |
Limit of quantification (ng) | 31.57 |
Robustness | Robust |
Ruggedness | |
Analyst-I (mean ± SD) | 101.63 ± 0.45 |
Analyst-I (mean ± SD) | 101.69 ± 0.70 |
Analysis of pharmaceutical preparation (mean ± SD) | 100.03 ± 1.63 |