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Table 1 Level of independent variables selected in Plackett-Burman design for screening the independent variables

From: Application of Plackett-Burman and central composite designs for screening and optimization of factor influencing the chromatographic conditions of HPTLC method for quantification of efonidipine hydrochloride

Sr. No.

Independent variables

Unit

Experimental value

Low (− 1)

High (+ 1)

1

Wavelength

nm

248

254

2

Saturation time

min

15

25

3

Volume of dichloromethane

mL

1.5

2.5

4

Volume of triethylamine

mL

0.3

0.7

5

Development distance

cm

7.5

8.5

6

Activation of plate

min

8.0

12