Table 3 Validation data set of SNAP-8 by LC-MS/MS
Analyte | Calibration range (ng/mg of microneedle of patch) | Linearity (r) | LODa | LOQb | Repeatabilityc (%) | Accuracyd (%) | Recoverye (%) | ||
|---|---|---|---|---|---|---|---|---|---|
Added (ng/mg of microneedle of patch) | |||||||||
0.05 | 0.1 | 0.05 | 0.1 | 0.125 | |||||
Acetyloctapeptide-3 (SNAP-8) | 0.0125–0.125 | 0.9971 | 0.0025 | 0.0125 | 0.12 | 0.02 | 1.44 | − 1.68 | 76.7 |