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Table 2 Details of the powdered mixtures prepared

From: On-spot quantification of modafinil in generic medicines purchased from the Internet using handheld Fourier transform-infrared, near-infrared and Raman spectroscopy

DN Modafinil tablet amount (mg) Diluent Diluent amount (mg) Total weight (mg) API (% m/m)
M1V1 201.3 LAC 0 201.3 62.5
M1V2 181.6 LAC 19.6 201.2 56.4
M1V3 168.5 LAC 32.6 201.1 52.4
M1V4 159.5 LAC 43.3 202.8 49.1
M1V5 151.2 LAC 53.1 204.3 46.2
M1V6 129 LAC 71.7 200.7 40.2
M1V7 110.9 LAC 90.6 201.5 34.4
M1V8 99.3 LAC 98.9 198.2 31.3
M1V9 81 LAC 119.9 201 25.2
M1V10 71.8 LAC 129.7 201.5 22.3
M1V11 50.8 LAC 150 200.8 15.8
M1V12 30.6 LAC 170.7 201.3 9.5
M1V13 0 LAC 199.6 199.6 0
M2V1 169.6 LAC/POV 30.6 200.2 52.9
M2V2 163 LAC/POV/MgS 52.4 215.4 47.3
M2V3 121.9 LAC/POV/MgS/MAI 79.4 201.3 37.8
M2V4 104.1 LAC/POV/MgS/MAI/MCC 97.2 201.3 32.3
M2V5 76.8 LAC/MCC/NaCMC 134.9 211.7 22.7
M2V6 51.8 LAC/POV/MgS/MAI/MCC/NaCMC 158.9 210.7 15.4
M3V1 201.3 0 0 201.3 62.5
M3V2 180.3 LAC 43.2 223.5 50.1
M3V3 134.4 POV 78.8 213.1 39.4
M3V4 100.7 MgS 97.2 197.8 31.8
M3V5 87.2 MAI 128 215.2 25.3
M3V6 71 MCC 149.1 220.1 20.2
M3V7 52.7 NaCMC 154.5 207.2 15.9
  1. DN dilution number, M1 modafinil lactose dilution, M2 modafinil excipients dilution, M3 modafinil excipients sequential addition, LAC lactose, POV povidone, MgS magnesium stearate, MAI maize starch, MCC microcrystalline cellulose, NaCMC sodium carboxymethylcellulose