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Table 3 Minimal inhibitory concentration (MIC) of KR-12-pa, methylparaben, Scutellaria baicalensis extract, and melittin

From: NMR structure and bactericidal activity of KR-12 analog derived from human LL-37 as a potential cosmetic preservative

Strain

MIC (μg/mL)

KR-12-pa

Methyl paraben

Scutellaria baicalensis extract

Melittin

Gram-negative

Escherichia coli (KCTC 1682)

1.6

> 205

> 205

5.7

Salmonella typhimurium (KCTC 1926)

1.6

> 205

> 205

5.7

Pseudomonas aeruginosa (KCTC 1637)

3.2

> 205

> 205

5.7

Gram-positive

Staphylococcus aureus (KCTC 1621)

3.2

> 205

> 205

2.8

Bacillus subtilis (KCTC 3068)

3.2

> 205

> 205

5.7

Staphylococcus epidermidis (KCTC 1917)

3.2

> 205

> 205

5.7

Yeast

Candida glabrata (KCTC 7219)

12.8

> 205

> 205

22.4