Journal of Analytical Science and Technology

Table 4 Robustness testing^a of the adopted chromatographic methods for the simultaneous estimation of SBR and LPV

From: Simultaneous chromatographic analysis of Sofosbuvir/Ledipasvir in their combined dosage form: an application to green analytical chemistry

HPTLC-densitometric method
Condition	SBR				LPV
Condition	R_f	T		R_s^b	R_f	T
Mobile phase ratio (± 0.2 mL)	1.501	1.315		1.513	1.412	1.543
RP HPLC-UV method
Condition	SBR				LPV
Condition	R_t	T	N	R_s^b	R_t	T	N
Mobile phase ratio (± 2.0 mL)	0.796	0.317	0.398	1.573	0.843	0.486	1.059
pH of of the mobile phase (± 0.1 unit)	0.264	0.341	0.486	1.583	0.386	0.563	1.251

^aRSD% (n = 6)
^bResolution to LPV

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