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Table 5 Mean pharmacokinetic parameters of lenalidomide in 12 human volunteers

From: Development and validation of a liquid chromatography-tandem mass spectrometric method for the determination of lenalidomide in human plasma and its application on bioequivalence studies

Parameters

Reference (mean ± SD)

Test (mean ± SD)

Cmax (h)

338.73 ± 87.44

390.50 ± 144.47

AUC0–t (ng.h/mL)

1669.63 ± 620.29

1883.66 ± 757.12

AUC0–∞ (ng.h/mL)

1792.35 ± 681.77

1982.24 ± 791.43

tmax (h)

2.03 ± 0.70

2.08 ± 0.61

kel

0.26 ± 0.05

0.26 ± 0.05

t1/2 (h)

2.80 ± 0.64

2.79 ± 0.58