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Table 5 Mean pharmacokinetic parameters of lenalidomide in 12 human volunteers

From: Development and validation of a liquid chromatography-tandem mass spectrometric method for the determination of lenalidomide in human plasma and its application on bioequivalence studies

ParametersReference (mean ± SD)Test (mean ± SD)
Cmax (h)338.73 ± 87.44390.50 ± 144.47
AUC0–t (ng.h/mL)1669.63 ± 620.291883.66 ± 757.12
AUC0–∞ (ng.h/mL)1792.35 ± 681.771982.24 ± 791.43
tmax (h)2.03 ± 0.702.08 ± 0.61
kel0.26 ± 0.050.26 ± 0.05
t1/2 (h)2.80 ± 0.642.79 ± 0.58