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Table 4 Stability data of daclatasvir from rat serum

From: Ionic liquid-based vortex-assisted DLLME followed by RP-LC-PDA method for bioassay of daclatasvir in rat serum: application to pharmacokinetics

Storage conditions Added conc. (μg/mL) Calculated conc. (μg/mL) (mean ± S.D) RE (%)
Ambient (6 h) 0.05 0.07 ± 1.92 2.4
  0.1 0.12 ± 2.34 2.9
2.0 1.95 ± 3.02 2.5
5.0 2.95 ± 3.01 2.3
7.5 7.52 ± 3.83 3.5
3 freeze (− 20 °C) thaw cycles 0.05 0.04 ± 3.07 2.1
  0.1 0.09 ± 4.41 2.6
2.0 2.05 ± 3.80 3.1
5.0 2.90 ± 3.02 2.4
7.5 7.48 ± 4.29 4.2
2–10 °C, 3 days 0.05 0.06 ± 3.54 2.9
  0.1 0.13 ± 4.07 3.8
2.0 1.96 ± 3.45 2.4
5.0 2.90 ± 3.07 2.4
7.5 7.42 ± 4.21 3.7
Autosampler stability (24 h) 0.05 0.08 ± 2.90 3.2
  0.1 0.15 ± 3.42 2.9
2.0 2.10 ± 2.61 2.2
5.0 2.91 ± 3.03 2.4
7.5 7.44 ± 4.22 3.8
  1. S.D standard deviation, RE relative error (n = 6)