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Table 6 Stability studies for chlorthalidone (n = 5)

From: An approach to select linear regression model in bioanalytical method validation

Level Stability at room temperature Stability at − 20 °C Freeze thaw (FT) stability
% Nominal % RSD % Nominal % RSD % Nominal % RSD
2 h 4 h 6 h 2 h 4 h 6 h 10 days 20 days 30 days 10 days 20 days 30 days FT1 FT2 FT3 FT1 FT2 FT3
LQC 98.84 98.105 98.38 2.31 1.74 1.546 96.74 96.968 98.91 1.03 3.51 1.65 90.910 95.06 98.81 1.18 1.54 1.98
HQC 100.8 100.6 100.6 2.48 0.48 1.678 100.50 100.31 100.7 0.36 2.81 0.23 100.49 100.4 100.45 0.17 0.87 0.28