Table 2 Components, compositions, and pharmaceutical functions of rivastigmine tartrate and donepezil HCl effervescent mini buccal tablets
Ingredient | Donepezil | Rivastigmine | Rivastigmine | Pharmaceutical |
|---|---|---|---|---|
Buccal tablet | Buccal tablet (F1) | Buccal tablet (F2) | Function | |
Rivastigmine tartrate | – | 9.6 | 9.6 | API |
Donepezil HCl | 10.7 | – | – | API |
Malic acid | 20.71 | 20.71 | 20.71 | Acid |
Sodium bicarbonate | 25.95 | 25.95 | 25.95 | Base |
Splenda | 33.5 | 33.5 | 33.5 | Sweetening |
Sodium benzoate | 0.24 | 0.24 | 0.24 | Preservative |
PEG 8000 | 10.65 | 10.65 | 10.65 | Binder |
Magnesium stearate | – | 2.37 | – | Lubricant |
Tartaric acid | 3.4 | – | 3.4 | Lubricant |
Total Weight | 107.2 | 103.9 | 106.53 |