Fig. 2From: Investigating effect of water of hydration on active pharmaceutical ingredients in a water-sensitive dosage formThe FT-IR spectra of donepezil HCl. a The donepezil HCl crystals and the crushed tablet after storage at controlled RT, 60% RH vs. 40 °C, and 25% RH for 1 month. Apparently, the water of hydration had reacted with the acid and base excipients giving off carbon dioxide. b SplendaBack to article page