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Table 1 Accuracy of quantifying cathinone in plasma using standard addition method

From: Detection of cathinone and mephedrone in plasma by LC-MS/MS using standard addition quantification technique

Matrix

Calibration curve

X value when Y = 0

Calculated drug concentration (ng/ml)

% Recovery

Solvent

Y = 15,056× + 11,361

0.755 ng/ml

  

Plasma with 0 ng/ml cathinone

Y = 15,765

X + 116,422

7.38 ng/ml

  

Plasma with 10 ng/ml cathinone

Y = 12,855

X + 271,850

21.15 ng/ml

21.15–7.38 = 13.77 ng/ml

13.77/10 = 137.7%

Plasma with 33 ng/ml cathinone

Y = 14,171

X + 542,465

38.28 ng/ml

38.28–7.38 = 30.90 ng/ml

30.90/33 = 93.6%

Plasma with 100 ng/ml cathinone

Y = 14,906

X + 1,653,920

110.96 ng/ml

110.96–7.38 = 103.57 ng/ml

103.57/100 = 103.6%