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Table 6 Slope, permeability coefficient, and flux values for the formulations (in vitro and ex vivo studies)

From: Formulation and characterization of transdermal patches for controlled delivery of duloxetine hydrochloride

Formulation code

In vitro studies

Ex vivo studies

Slope

Permeability coefficient (cm/h)

Flux (μg/cm2/h)

Slope

Permeability coefficient (cm/h)

Flux (μg/cm2/h)

A1

0.554

0.0122

176.43

0.435

0.0095

138.53

A2

0.536

0.0118

170.70

0.39

0.0085

124.20

A3

0.536

0.0118

170.70

0.349

0.0076

111.14

A4

0.499

0.0109

158.91

0.316

0.0069

100.63

B1

0.557

0.0122

177.38

0.405

0.0089

128.98

B2

0.524

0.0115

166.87

0.377

0.0083

120.06

B3

0.476

0.0104

151.59

0.345

0.0075

109.87

B4

0.494

0.0108

157.32

0.321

0.0070

102.22

C1

0.549

0.0120

174.84

0.518

0.0114

164.96

C2

0.565

0.0124

179.93

0.493

0.0108

157.00

C3

0.524

0.0115

166.87

0.485

0.0106

154.45

C4

0.521

0.0114

165.92

0.437

0.0096

139.17