Table 2 Physical characterization data for the transdermal patches
Formulation code | Weighta(mg) ± SD | Thicknessa(mm) ± SD | Foldingaendurance ± SD | Diametera(cm) ± SD | Area (cm2) | Flatness (%) | Surface pH |
|---|---|---|---|---|---|---|---|
A1 | 207.30 ± 2.68 | 0.053 ± 0.001 | 306.3 ± 2.52 | 4.03 ± 0.03 | 12.56 | 100 | 5.43 |
A2 | 168.10 ± 3.64 | 0.050 ± 0.002 | 302.0 ± 1.73 | 4.06 ± 0.02 | 12.87 | 100 | 5.48 |
A3 | 201.10 ± 2.48 | 0.048 ± 0.001 | 304.6 ± 2.51 | 4.10 ± 0.05 | 13.51 | 100 | 5.66 |
A4 | 160.70 ± 2.32 | 0.047 ± 0.001 | 300.0 ± 1.73 | 4.03 ± 0.02 | 12.87 | 100 | 5.56 |
B1 | 240.80 ± 2.74 | 0.054 ± 0.001 | 308.6 ± 2.08 | 4.06 ± 0.02 | 13.19 | 100 | 5.71 |
B2 | 184.00 ± 2.16 | 0.048 ± 0.001 | 308.0 ± 2.64 | 4.06 ± 0.02 | 12.87 | 100 | 5.74 |
B3 | 178.70 ± 1.34 | 0.050 ± 0.002 | 306.6 ± 2.08 | 4.08 ± 0.02 | 12.87 | 100 | 5.63 |
B4 | 161.80 ± 2.21 | 0.050 ± 0.001 | 303.3 ± 1.53 | 4.05 ± 0.04 | 12.87 | 100 | 5.67 |
C1 | 209.70 ± 4.01 | 0.049 ± 0.001 | 301.1 ± 2.31 | 4.11 ± 0.02 | 13.51 | 100 | 5.47 |
C2 | 203.70 ± 3.77 | 0.052 ± 0.001 | 298.0 ± 2.64 | 4.06 ± 0.02 | 13.19 | 100 | 5.47 |
C3 | 245.90 ± 2.45 | 0.053 ± 0.002 | 302.6 ± 2.08 | 4.06 ± 0.02 | 12.87 | 100 | 5.67 |
C4 | 207.10 ± 2.77 | 0.050 ± 0.001 | 298.3 ± 2.08 | 4.06 ± 0.03 | 13.19 | 100 | 5.52 |