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Table 1 Formulae and composition of formulated transdermal systems of duloxetine HCl

From: Formulation and characterization of transdermal patches for controlled delivery of duloxetine hydrochloride

HPMC grade

Water content (%)

Methanol content (%)

Percent PEG 400

Concentration of HPMC (%)

Code no.

15 M CR

30

70

5

1.0

A1

15 M CR

30

70

–

1.0

A2

15 M CR

30

70

5

1.5

A3

15 M CR

30

70

–

1.5

A4

100 M

30

70

5

1.0

B1

100 M

30

70

–

1.0

B2

100 M

30

70

5

1.5

B3

100 M

30

70

–

1.5

B4

4 CM

30

70

5

1.0

C1

4 CM

30

70

–

1.0

C2

4 CM

30

70

5

1.5

C3

4 CM

30

70

–

1.5

C4