A LC–MS/MS method with column coupling technique for simultaneous estimation of lamivudine, zidovudine, and nevirapine in human plasma

Journal of Analytical Science and Technology

Table 7 Extended accuracy and precision analysis

Analyte	QC sample	Actual conc. (ng/ml)	Estimated conc. (ng/ml)	Accuracy (%)	% CV
Lamivudine	LQC	27.53	26.88	97.65	2.72
Lamivudine	HQC	1146.90	1153.16	100.55	2.52
Zidovudine	LQC	29.84	29.07	97.42	4.71
Zidovudine	HQC	1243.43	1211.79	97.46	2.12
Nevirapine	LQC	44.29	44.85	101.25	2.28
Nevirapine	HQC	1845.48	1815.04	98.35	2.47