Journal of Analytical Science and Technology

Table 3 Accuracy and precision of analysis in the quality-control samples

From: A LC–MS/MS method with column coupling technique for simultaneous estimation of lamivudine, zidovudine, and nevirapine in human plasma

			Intraday			Interday
Analyte	QC sample	Actual conc. (ng/ml)	Estimated conc. (ng/ml)	Accuracy (%)	% CV	Estimated conc. (ng/ml)	Accuracy (%)	% CV
Lamivudine	LLOQ	9.63	10.05	104.36	3.01	9.33	96.83	7.12
	LQC	27.53	28.06	101.95	2.01	27.92	101.43	3.20
	MQC	458.76	457.46	99.72	2.26	457.49	99.72	1.92
	HQC	1146.90	1152.58	100.49	1.67	1157.65	100.94	2.49
Zidovudine	LLOQ	10.44	9.81	93.95	5.77	10.30	98.64	8.19
	LQC	29.84	27.83	93.25	3.52	29.59	99.15	5.59
	MQC	497.37	483.61	97.23	2.56	494.18	99.36	2.75
	HQC	1243.43	1227.03	98.68	2.42	1244.60	100.09	3.42
Nevirapine	LLOQ	15.24	15.06	98.86	2.96	15.60	102.40	3.84
	LQC	44.29	45.00	101.60	1.89	45.74	103.28	2.83
	MQC	738.19	748.98	101.46	0.86	747.47	101.26	2.24
	HQC	1845.48	1878.40	101.78	1.17	1864.04	101.01	2.59

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