Fig. 1

Representative chromatograms of ifosfamide, cyclophosphamide, paclitaxel, and the internal standard hexamethylphosphoramide. a A blank solution. b A standard solution containing (1) hexamethylphosphoramide (20 μg/mL), (2) ifosfamide and (3) cyclophosphamide (10 μg/mL), and (4) paclitaxel (9 μg/mL). c A spiked wipe sample containing (1) hexamethylphosphoramide (20 μg/mL), (2) ifosfamide (4 μg/mL), (3) cyclophosphamide (5 μg/mL), and (4) paclitaxel (7 μg/mL). d A field wipe sample containing (1) hexamethylphosphoramide (20 μg/mL), (2) ifosfamide (2.5 μg/mL), and (3) paclitaxel (4.8 μg/mL). Flow rate 1.0 mL/min, gradient elution (see Table 1) and detection at 195 nm