Table 7 Pharmacokinetic parameters of lovastatin, after administration of an oral dose of 40 mg of lovastatin test and reference formulation of 31 healthy human volunteers
(Mean ± SD) | ||
|---|---|---|
Parameters | Test | Reference |
Tmax (h) | 3.12 ± 1.28 | 2.89 ± 1.26 |
Cmax (ng/mL) | 16.13 ± 7.18 | 16.68 ± 7.36 |
AUC0→t(h.ng/mL) | 81.25 ± 34.53 | 88.73 ± 37.66 |
t 1/2 (h) | 3.12 ± 1.28 | 2.89 ± 1.26 |