Table 5 Relative matrix effect of lovastatin
Plasma lot | LOQQC (0.122 ng/mL) | HQC (28.716 ng/mL | ||
|---|---|---|---|---|
Mean calculated concentrationa (% CV)b | % bias | Mean calculated concentrationa (% CV)b | % bias | |
Lot-1 | 0.121 (1.2) | −0.82 | 28.799 (0.20) | 0.29 |
Lot-2 | 0.122 (5.2) | 0.00 | 28.632 (0.00) | −0.29 |
Lot-3 | 0.126 (4.5) | 3.28 | 28.145 (1.80) | −1.99 |
Lot-4 | 0.118 (0.6) | −6.56 | 29.527 (0.70) | 1.14 |
Lot-5c | 0.114 (4.4) | −3.28 | 29.042 (0.80) | 2.82 |
Lot-6d | 0.121 (4.1) | −0.82 | 28.960 (0.40) | 0.85 |