From: Performance characteristics of biodistribution of 99mTc-cefprozil for in vivo infection imaging
Percentage of injected dose/organs at different time intervals (h) | ||||||||
---|---|---|---|---|---|---|---|---|
Organs and body fluids | Turpentine oil | S. aureus | ||||||
15 min | 30 min | 2 h | 4 h | 15 min | 30 min | 2 h | 4 h | |
Inflamed muscle | 0.90 ± 0.01 | 1.11 ± 0.02 | 1.20 ± 0.03 | 0.90 ± 0.02 | 0.95 ± 0.01 | 1.15 ± 0.01 | 1.21 ± 0.02 | 1.36 ± 0.01 |
Normal muscle | 0.63 ± 0.02 | 0.37 ± 0.01 | 0.33 ± 0.01 | 0.45 ± 0.01 | 0.38 ± 0.01 | 0.26 ± 0.02 | 0.22 ± 0.01 | 0.37 ± 0.02 |
Blood | 15.7 ± 0.21 | 9.8 ± 0.13 | 2.90 ± 0.21 | 1.50 ± 0.21 | 12.5 ± 0.13 | 8.64 ± 0.21 | 2.5 ± 0.12 | 1.1 ± 0.12 |
Kidneys | 11.15 ± 0.63 | 20.55 ± 0.31 | 10.42 ± 0.12 | 9.45 ± 0.23 | 13.7 ± 0.14 | 17.9 ± 0.33 | 11.2 ± 0.14 | 8.25 ± 0.41 |
Liver | 12 ± 0.11 | 10.22 ± 0.11 | 8.24 ± 0.11 | 5.75 ± 0.21 | 15.33 ± 0.11 | 11.42 ± 0.11 | 7.8 ± 0.11 | 6.9 ± 0.11 |
Spleen | 5.1 ± 0.11 | 3.0 ± 0.11 | 2.7 ± 0.12 | 1.9 ± 0.21 | 4.4 ± 0.21 | 3.8 ± 0.12 | 3.1 ± 0.21 | 2.5 ± 0.13 |
Intestine | 8.72 ± 0.11 | 6.12 ± 0.11 | 5.26 ± 0.13 | 3.31 ± 0.21 | 5.37 ± 0.12 | 4.6 ± 0.13 | 3.1 ± 0.21 | 2.12 ± 0.11 |
Stomach | 1.12 ± 0.11 | 1.28 ± 0.11 | 1.9 ± 0.01 | 1.33 ± 0.01 | 1.43 ± 0.01 | 2.1 ± 0.02 | 1.8 ± 0.02 | 1.12 ± 0.06 |
Lungs | 1.23 ± 0.12 | 1.5 ± 0.13 | 1.48 ± 0.11 | 1.37 ± 0.02 | 2.1 ± 0.01 | 1.7 ± 0.11 | 1.2 ± 0.02 | 1.4 ± 0.02 |
Heart | 2.1 ± 0.21 | 1.61 ± 0.01 | 1.1 ± 0.11 | 1.2 ± 0.12 | 1.8 ± 0.11 | 1.2 ± 0.01 | 1.6 ± 0.11 | 1.5 ± 0.02 |
Bone | 2.2 ± 0.12 | 2.16 ± 0.21 | 2.13 ± 0.32 | 2.3 ± 0.13 | 1.94 ± 0.31 | 1.45 ± 0.03 | 0.9 ± 0.02 | 1.52 ± 0.13 |
Urine | 9.23 ± 0.4 | 12.6 ± 0.4 | 21.3 ± 0.63 | 30.5 ± 0.83 | 10.5 ± 0.14 | 13.15 ± 1.14 | 28.86 ± 0.84 | 34.54 ± 0.15 |
T/NT | 1.43 ± 0.01 | 3.0 ± 0.04 | 3.6 ± 0.11 | 2.0 ± 0.01 | 2.5 ± 0.01 | 4.4 ± 0.16 | 5.5 ± 0.12 | 3.70 ± 0.03 |