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Table 1 Biodistribution of 99m Tc-cefprozil in Staphylococcus aureus and turpentine oil-inflamed mice at different time intervals

From: Performance characteristics of biodistribution of 99mTc-cefprozil for in vivo infection imaging

 

Percentage of injected dose/organs at different time intervals (h)

Organs and body fluids

Turpentine oil

S. aureus

15 min

30 min

2 h

4 h

15 min

30 min

2 h

4 h

Inflamed muscle

0.90 ± 0.01

1.11 ± 0.02

1.20 ± 0.03

0.90 ± 0.02

0.95 ± 0.01

1.15 ± 0.01

1.21 ± 0.02

1.36 ± 0.01

Normal muscle

0.63 ± 0.02

0.37 ± 0.01

0.33 ± 0.01

0.45 ± 0.01

0.38 ± 0.01

0.26 ± 0.02

0.22 ± 0.01

0.37 ± 0.02

Blood

15.7 ± 0.21

9.8 ± 0.13

2.90 ± 0.21

1.50 ± 0.21

12.5 ± 0.13

8.64 ± 0.21

2.5 ± 0.12

1.1 ± 0.12

Kidneys

11.15 ± 0.63

20.55 ± 0.31

10.42 ± 0.12

9.45 ± 0.23

13.7 ± 0.14

17.9 ± 0.33

11.2 ± 0.14

8.25 ± 0.41

Liver

12 ± 0.11

10.22 ± 0.11

8.24 ± 0.11

5.75 ± 0.21

15.33 ± 0.11

11.42 ± 0.11

7.8 ± 0.11

6.9 ± 0.11

Spleen

5.1 ± 0.11

3.0 ± 0.11

2.7 ± 0.12

1.9 ± 0.21

4.4 ± 0.21

3.8 ± 0.12

3.1 ± 0.21

2.5 ± 0.13

Intestine

8.72 ± 0.11

6.12 ± 0.11

5.26 ± 0.13

3.31 ± 0.21

5.37 ± 0.12

4.6 ± 0.13

3.1 ± 0.21

2.12 ± 0.11

Stomach

1.12 ± 0.11

1.28 ± 0.11

1.9 ± 0.01

1.33 ± 0.01

1.43 ± 0.01

2.1 ± 0.02

1.8 ± 0.02

1.12 ± 0.06

Lungs

1.23 ± 0.12

1.5 ± 0.13

1.48 ± 0.11

1.37 ± 0.02

2.1 ± 0.01

1.7 ± 0.11

1.2 ± 0.02

1.4 ± 0.02

Heart

2.1 ± 0.21

1.61 ± 0.01

1.1 ± 0.11

1.2 ± 0.12

1.8 ± 0.11

1.2 ± 0.01

1.6 ± 0.11

1.5 ± 0.02

Bone

2.2 ± 0.12

2.16 ± 0.21

2.13 ± 0.32

2.3 ± 0.13

1.94 ± 0.31

1.45 ± 0.03

0.9 ± 0.02

1.52 ± 0.13

Urine

9.23 ± 0.4

12.6 ± 0.4

21.3 ± 0.63

30.5 ± 0.83

10.5 ± 0.14

13.15 ± 1.14

28.86 ± 0.84

34.54 ± 0.15

T/NT

1.43 ± 0.01

3.0 ± 0.04

3.6 ± 0.11

2.0 ± 0.01

2.5 ± 0.01

4.4 ± 0.16

5.5 ± 0.12

3.70 ± 0.03