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Table 6 Possible structures and characterizations of complexes

From: Spectroscopic characterization of in vitro interactions of cetirizine and NSAIDS

Complex

Chemical structure

Appearance

Solubility

Melting point (°C)

Dic-cet

White crystalline

Soluble in methanol, chloroform, and acetonitrile

108

Mef-cet

Off-white amorphous

Soluble in methanol, chloroform, and acetonitrile

Decompose at 210

Mel-Cet

Off-white amorphous

Soluble in methanol, chloroform, and acetonitrile

230

Ibu-cet

Off-white amorphous

Soluble in methanol, chloroform, and acetonitrile

225

Flu-cet

White amorphous

Soluble in methanol, chloroform, and acetonitrile

110

  1. Dic-cet, diclofenac and cetirizine complex; Mef-cet, mefenamic acid and cetirizine complex; Mel-Cet, meloxicam and cetirizine complex; Ibu-cet, ibuprofen and cetirizine complex; Flu-cet, flurbiprofen and cetirizine complex.