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Table 5 Solution stability data of SHH and MAP PGIs at LOQ concentration

From: A selective and sensitive LC-MS/MS method for the simultaneous determination of twopotential genotoxic impurities in celecoxib

Parameter

SHH

MAP

Solution stability

  

 Theoretical concentration (ppm)

0.06

0.06

Percent recovery (n = 3)

  

 At 0 h

98.2 ± 0.94

96.2 ± 1.24

 At 12 h

101.4 ± 1.13

95.6 ± 0.91

 At 24 h

102.6 ± 0.82

96.4 ± 0.88

 At 48 h

99.8 ± 1.45

100.4 ± 1.36

  1. n, number of determinations.