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Table 6 Analysis of the investigated drugs (100.0 ng mL -1 ) in presence of some common excipients using the proposed spectrofluorimetric method

From: Spectrofluorimetric determination of certain antidepressant drugs in human plasma

Excipients

Amount Added μgmL -1

% Recovery d ± SD

  

Fluoxetine

Sertraline

Paroxetine

Thioridazine

Amineptine

Starch

50

100.07 ± 0.61

99.19 ± 0.72

99.85 ± 0.87

100.80 ± 0.78

101.29 ± 0.79

Lactose

50

98.21 ± 0.91

99.83 ± 0.63

98.78 ± 0.61

100.73 ± 0.71

98.12 ± 0.45

Mg stearate

50

101.25 ± 0.54

98.24 ± 1.25

101.58 ± 1.61

99.86 ± 0.33

101.62 ± 1.07

Gum acacia

50

99.25 ± 0.59

99.76 ±1.01

98.82 ± 0.86

100.28 ± 0.89

101.98 ± 0.49

Talc

50

100.38 ± 1.58

100.18 ±0.25

98.21 ± 0.67

99.70 ± 0.51

99.81 ± 0.34

  1. dAverage of three determinations.