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Table 6 Analysis of the investigated drugs (100.0 ng mL -1 ) in presence of some common excipients using the proposed spectrofluorimetric method

From: Spectrofluorimetric determination of certain antidepressant drugs in human plasma

Excipients Amount Added μgmL -1 % Recovery d ± SD
   Fluoxetine Sertraline Paroxetine Thioridazine Amineptine
Starch 50 100.07 ± 0.61 99.19 ± 0.72 99.85 ± 0.87 100.80 ± 0.78 101.29 ± 0.79
Lactose 50 98.21 ± 0.91 99.83 ± 0.63 98.78 ± 0.61 100.73 ± 0.71 98.12 ± 0.45
Mg stearate 50 101.25 ± 0.54 98.24 ± 1.25 101.58 ± 1.61 99.86 ± 0.33 101.62 ± 1.07
Gum acacia 50 99.25 ± 0.59 99.76 ±1.01 98.82 ± 0.86 100.28 ± 0.89 101.98 ± 0.49
Talc 50 100.38 ± 1.58 100.18 ±0.25 98.21 ± 0.67 99.70 ± 0.51 99.81 ± 0.34
  1. dAverage of three determinations.