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Table 1 Regression equations for the reaction rate and fixed time methods for the determination of pregabalin

From: Kinetic spectrophotometric determination of an important pharmaceutical compound, pregabalin

Method

Regression equation

r 2

Reaction rate method

Rate = 2.8 × 10-4+ 2.48 × 10-4 × drug concentration

0.999

Fixed time method, time (min)

  

 5

A = 0.00106 + 0.00123 × drug concentration

0.999

 10

A = -0.0032 + 0.00111 × drug concentration

0.999

 15

A = -0.0038 + 0.00103 × drug concentration

0.999

 20

A = 0.0052 + 7.2 × 10-4 × drug concentration

0.993

 25

A = 0.0036 + 6.4 × 10-4 × drug concentration

0.999

 30

A = 0.0034 + 5.6 × 10-4 × drug concentration

0.992

 35

A = 0.003 + 4.9 × 10-4 × drug concentration

0.989

 40

A = 0.0032 + 4.4 × 10-4 × drug concentration

0.984

 45

A = 0.0026 + 3.8 × 10-4 × drug concentration

0.979

 50

A = 0.0046 + 2.9 × 10-4 × drug concentration

0.993

  1. A Absorbance.
  2. The drug concentration is represented in μg/ml.