|
Linearity
|
1 to 20 μg/mL
|
|
Regression equation
|
AUC = 79,991X − 64,340
|
|
Correlation coefficient
|
r2 = 0.999 ± 0.001, ±0.100
|
|
Range
|
5 to 15 μg/mL ± 1.08, ±0.51
|
|
Accuracy
|
100.11 ± 1.065, ±0.784
|
|
Precision
| |
|
Repeatability
|
99.94 ± 0.742, ±0.482
|
|
Intermediate precision
| |
|
Inter-day
|
100.08 ± 0.825, ±0.091
|
|
Analyst to analyst
|
99.89 ± 0.929, ±0.027
|
|
Robustness
| |
|
Temperature (20°C, 25°C and 30°C)
|
99.91 ± 0.816, ±0.089
|
|
Formic acid concentration (±5%)
|
100.06 ± 0.794, ±0.296
|
|
LOQ
|
5 ng/mL ± 1.098, ±0.566
|
|
LOD
|
0.5 ng/mL ± 1.691, ±0.295
|
|
Specificity
|
Ascertained by analysing standard drug and degraded sample of equivalent concentration
|
