Fig. 15From: Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challengesDetermination of mAb:Ag binding stoichiometries. a–d mumAb was analyzed at 5 μM either a alone or in presence of b 5 μM, c 10 μM, and d 40 μM JAM-A IB. e–h hzmAb was analyzed at 5 μM either e alone or in presence of f 5 μM, g 10 μM, and h 40 μM JAM-A IB. i–l hzFab was analyzed at 10 μM either i alone or in presence of j 5 μM, k 10 μM and l 40 μM JAM-A IB. Reprinted with permission from Ref (Atmanene et al. 2009). Copyright 2014 American Chemical SocietyBack to article page