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Journal of Analytical Science and Technology
Fig. 7 | Journal of Analytical Science and Technology

Fig. 7

From: Synthesis and evaluation of small molecule-based derivatives as inhibitors of polo-box domain of polo-like kinase-1

Fig. 7

Evaluation of in vivo anticancer effect of 1. a The line graph represents the change in tumor volume caused by 1 and BI2536 (5 mg/kg of body weight). Tumor size changes are observed at 2- or 3-day intervals and values are expressed as mean ± standard deviation (n = 3). Tumor volume = length × width × height, mm3. ***p < 0.001, ****p < 0.0001 b Body weight changes in the PBS, BI2536, and 1 treated groups up to 21 days are expressed in %. c Tumors picture of change in size

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