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Fig. 6 | Journal of Analytical Science and Technology

Fig. 6

From: Synthesis and evaluation of small molecule-based derivatives as inhibitors of polo-box domain of polo-like kinase-1

Fig. 6

Fluorescence images of apoptosis using fluorescence microscope (× 100 magnification, scale bar: 100 μm). a HeLa cells were treated with BI2536 (200 nM) and its derivatives (200 μM) for 24 and 48 h and then stained with fluorescence apoptosis kit. Green and red fluorescence represent live and apoptosis cells, respectively. b Apoptosis cells are shown as red bar graphs that represent mean values. ***p < 0.001

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