Table 1 A brief comparison of the approach with former methods
Title | Mechanism | LOD | Labeling | Complexity | Ref |
|---|---|---|---|---|---|
The method | Target recycling + G-quadruplex-based signal generation | 4.4 fM | ThT | ||
Target recycling | Target recycling + PER | 49.4 fM | ThT | Two stage signal cycles | Li et al. (2022) |
RACE | RCA + CRISPR-Cas9 | 90 fM | FAM and BHQ | Multiple steps | Wang et al. (2020) |
Strand displacement | Strand displacement + Exo-III assisted signal process | 25.0 pM | FAM and BHQ | Multiple steps | Nie et al. (2023) |